Kyle Crocker

Kyle Crocker

Postdoctoral Fellow

The University of Chicago

Microbial communities are critically important biological systems, with ubiquitous impacts from human immunity to the global climate. The rapid improvement of sequencing technology over the last two decades was expected to give rise to a predictive microbiome science to facilitate design and control of these vital systems. However, building a predictive approach robust to the complexity of microbial communities in the wild remains a challenge. My research seeks to address this challenge by discovering simplicity in the structure of interactions in wild communities, employing a combination of statistics, experiments, and mathematical models. I expect that this low-dimensional interaction structure will provide a simple description that bypasses species-level complexity to foster a predictive understanding of these communities.

I am currently a Schmidt AI in Science Postdoctoral Fellow at the University of Chicago, advised by Seppe Kuehn in the Department of Ecology & Evolution and Center for Living Systems. Before beginning as a postdoc, I was a graduate student fellow at Ohio State, where I completed a PhD in physics with Ralf Bundschuh. My work in the Bundschuh lab focused on the use of statistical physics to build computational models of DNA-based systems.

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Research

Global patterns emerge from microbial interactions

How do global patterns in microbiome content arise?

Recent Publications

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Inferring resource competition in microbial communities from time series

The competition for resources is a defining feature of microbial communities. In many contexts, from soils to host-associated …

Microbial functional guilds respond cohesively to rapidly fluctuating environments

Microbial communities experience environmental fluctuations across timescales from rapid changes in moisture, temperature, or light …

Environmentally dependent interactions shape patterns in gene content across natural microbiomes

Sequencing surveys of microbial communities in hosts, oceans and soils have revealed ubiquitous patterns linking community composition …

Functional phases encode the response of the soil microbiome to environmental change

A major challenge in microbiome research is understanding how natural communities respond to environmental change. The ecological, …

High-force application by a nanoscale DNA force spectrometer

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